CCW16

产品名称：

2361138-33-0
CCW16
E3 ubiquitin ligase ligand
N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide
RNF4-targeting ligand
Ligand for PROTAC research

产品介绍：

产品说明

应用

CCW16 is targeting ligand for the E3 ubiquitin ligase RNF4 (RING finger protein 4) and can be used in targeted protein degradation (TPD) research or in the synthesis of protein degraders. Learn more about proteolysis-targeting chimeras (PROTAC degraders) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation.

其他说明

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Targeted Protein Degradation by Small Molecules

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₂₂H₂₀ClNO₃
分子量	381.85

产品性质

质量水平	100
测定	≥95%
形式	powder
储存温度	2-8℃
SMILES string	COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1 COC1=CC=C(OC2=CC=C(N(CC3=CC=CC=C3)C(CCl)=O)C=C2)C=C1

安全信息

象形图
警示用语：	Warning
危险声明	H410
预防措施声明	P273 - P391 - P501
危险分类	Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable