产品说明
应用
The Ritter lab has developed a new method for direct labeling of polypeptides with the [18F]fluoride radiolabel. This Fmoc-protected ruthenium tyrosine is first incorporated into peptides, which is amenable to standard solid-phase peptide synthesis (SPPS) and is tolerant of all 20 canonical amino acids. Subsequent replacement of a single hydrogen with fluorine-18, with only minimal perturbation of the peptide structure, results in a site-specific, radiolabeled peptide tracer for use with positron emission tomography (PET) imaging in the study of various biological applications.
注意
Research quantities limited to 10 g.
其他说明
Site-SpecificDeoxyfluorination of Small Peptides with [18F]Fluoride
法律信息
Patent Application EP18204755.5
This product is manufactured pursuant to a license with Studiengesellschaft Kohle mbH
基本信息
| 经验(实验)分子式 | C31H26F3NO7Ru |
| 分子量 | 682.61 |
| NACRES | NA.26 |
产品性质
| 形式 | powder |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| mp | >300 ℃ |
| application(s) | peptide synthesis |
| 官能团 | Fmoc |
| 储存温度 | 2-8℃ |
| SMILES string | O[C]1[CH][CH][C](CC(NC(OCC2C(C=CC=C3)=C3C4=C2C=CC=C4)=O)C(O)=O)[CH][CH]1.F[C-](F)F.O=C=O.[Ru+].c5cccc5 |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
