产品名称：
H-L-Photo-Proline hydrochloride
Photo-crosslinking amino acid
(S)-1,2,5-Triazaspiro[2.4]hept-1-ene-6-carboxylic acid
Photoprobe building block
Diazirine amino acid
Photo-Pro
产品介绍：
产品说明
应用
H-L-Photo-Proline HCl is a diazirine-containing proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907324.
其他说明
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis
Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)
基本信息
| 经验(实验)分子式 | C5H8ClN3O2 |
| 分子量 | 177.59 |
产品性质
| 测定 | ≥95% |
| 形式 | powder |
| reaction suitability | reaction type: solution phase peptide synthesis |
| application(s) | peptide synthesis |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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