产品说明
一般描述
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.
包装
250 μg in Glass bottle
Packaged under inert gas
生化/生理作用
Primary Target
caspase-8
Product does not compete with ATP.
Cell permeable: yes
Reversible: no
警告
Toxicity: Irritant (B)
序列
Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*
外形
A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.
重悬
Following initial thaw, aliquot and freeze (-20°C).
分析说明
single spot by TLC
其他说明
Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C30H43FN4O11 |
| 分子量 | 654.68 |
产品性质
| 质量水平 | 100 |
| 形式 | liquid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) protect from light |
| 运输 | wet ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | 188.6 °F - (refers to pure substance) |
| 闪点(C) | 87 ℃ - (refers to pure substance) |
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