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Nα-Tosyl-Phe Chloromethyl Ketone

品牌
Sigma-Aldrich
CAS
402-71-1
货号
616387
规格纯度
Irreversible inhibitor of chymotrypsin.
参考价格
1164.01 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
402-71-1
Nα-Tosyl-Phe Chloromethyl Ketone
TPCK
产品介绍:

产品说明

一般描述

This product has been discontinued.


Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC50 = 20 M).
Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharide (EC50 = 20 µM). Suggested working concentration is 10-100 µM.

包装

250 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Reversible: no
EC50 = 20 µM in blocking the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides.
Primary Target
chymotrypsin activity in preparations
Cell permeable: no

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.

其他说明

Fearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun.215, 721.
Weaver, V.M., et al. 1993. Biochem. Cell Biol.71, 488.
Murakami, T., et al. 1991. Biochim. Biophys. Acta1079, 279.
Nierodzik, M.L., et al. 1991. J. Clin. Invest.87, 229.
Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C17H18ClNO3S
分子量351.85
MDL编号MFCD00000935

产品性质

质量水平100
测定≥98% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white
溶解性ethanol: 5 mg/mL
methanol: 5 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C17H18ClNO3S/c1-13-7-9-15(10-8-13)23(21,22)19-16(17(20)12-18)11-14-5-3-2-4-6-14/h2-10,16,19H,11-12H2,1H3/t16-/m0/s1
InChI keyMQUQNUAYKLCRME-INIZCTEOSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H315 - H318 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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