<i>N</i>-(But-3-yn-1-yl)-2-(((2-oxo-2<i>H</i>-chromen-7-yl)oxy)methyl)acrylamide

产品名称：

N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide
Coumarin alkyne CoLDR probe

产品介绍：

产品说明

应用

N-(But-3-yn-1-yl)-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)acrylamide is a proteomic cysteine probe. As described in Reddi et al, the Nir London lab developed a-substituted N-alkynyl-methacrylamides for covalent ligand directed release chemistry (CoLDR). CoLDR represents a new type of acrylamide-based electrophiles for targeted covalent inhibitor discovery and design. Specifically this CoLDR probe is a coumarin derivative with a terminal alkyne for click chemistry.

其他说明

Chemical Biology Tools

Click Chemistry Reagents

基本信息

经验(实验)分子式	C₁₇H₁₅NO₄
分子量	297.31

产品性质

reaction suitability	reagent type: chemical modification reagent reaction type: click chemistry
质量水平	100
官能团	(Alkyne)
储存温度	2-8℃
SMILES string	O=C1OC2=CC(OCC(C(NCCC#C)=O)=C)=CC=C2C=C1

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable