(2 R )-3-羧基- N 、 N 、 N -三甲基-2-（1-氧代丙氧基）-1-丙胺内盐

产品名称：

20064-19-1
Propionyl-L-carnitine
Propanoyl-L-carnitine
(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt
L-Carnitine propionyl ester
C3-Carnitine
丙酰-L-肉碱
(2 R )-3-羧基- N 、 N 、 N -三甲基-2-（1-氧代丙氧基）-1-丙胺内盐
L -肉碱丙酰基酯
丙酰- L -肉碱
C3-肉碱

产品介绍：

产品说明

一般描述

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

应用

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

生化/生理作用

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

基本信息

经验(实验)分子式	C₁₀H₁₉NO₄
分子量	217.26
MDL编号	MFCD00870024
PubChem化学物质编号	329756246
NACRES	NA.26

产品性质

质量水平	100
测定	≥94.0% (HPLC)
形式	powder or crystals
旋光性	[α]/D -23±3°, c = 1 in H₂O
technique(s)	LC/MS: suitable
杂质	≤10% water (calcd. from elemental analysis)
颜色	white to off-white
储存温度	2-8℃
SMILES string	[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
InChI	1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChI key	UFAHZIUFPNSHSL-MRVPVSSYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable