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位置:首页 > 品牌 > Sigma-Aldrich > SILuTMMAb Mouse Stable-Isotope Labeled Monoclonal Antibody

SILuTMMAb Mouse Stable-Isotope Labeled Monoclonal Antibody

品牌
Sigma-Aldrich
货号
MSQC10
规格纯度
from mouse, recombinant, expressed in CHO cells
参考价格
4434.12 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
SILuTMMAb Mouse Stable-Isotope Labeled Monoclonal Antibody
产品介绍:

产品说明

一般描述

SILuMAb Mouse is a recombinant, stable isotope-labeled, mouse monoclonal antibody which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in CHO cells, SILuMAb Mouse is designed to be used as a universal internal standard for bioanalysis of monoclonal murine antibodies in animal pharmacokinetics (PK) studies.

SILuMAb Mouse is an IgG1 antibody with a kappa light chain. Because of overlap with common sequences in the Fc region with candidate murine antibodies, SILuMAb Mouse provides universal utility, and thus, eliminates the need to produce candidate-specific internal standards.

外形

Each vial of SILuMAb Mouse contains the labeled antibody lyophilized from a solution of phosphate buffered saline. Vial content was determined by measuring A280 and using an extinction coefficient (E0.1%) of 1.4.

制备说明

Produced utilizing enriched media containing stable isotope labeled amino acids such as [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in CHO cells, SILuMAb Mouse is designed to be used as a universal internal standard for bioanalysis of monoclonal murine antibodies in animal pharmacokinetics (PK) studies

重悬

SILuMAb Mouse recovery is maximized when 0.1% formic acid is used for reconstitution of the lyophilized product.
Reconstitution with other solvents may reduce recovery. Do not freeze after reconstitution.

  • Briefly centrifuge the vial at ~10,000 × g to collect the product at the bottom of the vial.
  • Add 500 μL of ultrapure water containing 0.1% formic acid to the vial.
  • Mix the contents by gently inverting the vial a minimum of 5 times.
  • Allow the vial to stand at room temperature for at least 15 minutes and repeat mixing by inversion.

法律信息

SILu is a trademark of sigma-aldrich Co. LLC

产品性质

质量水平200
生物来源mouse
重组expressed in CHO cells
antibody product typeprimary antibodies
测定≥90% (SDS-PAGE)
包装vial of 100 μg
运输wet ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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