产品说明
应用
Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.
Learn More at the Professor and Product Portal of Professor Phil S. Baran.
包装
100 mg in glass insert
基本信息
经验(实验)分子式 | C7H12F2N3NaO2S |
分子量 | 263.24 |
PubChem化学物质编号 | 329765744 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | 95% |
reaction suitability | reagent type: catalyst reaction type: C-H Activation reagent type: linker |
储存温度 | 2-8℃ |
SMILES string | [Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-] |
InChI | 1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1 |
InChI key | FFNHIEJQAMGBCZ-UHFFFAOYSA-M |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich