产品说明
应用
Thiophosphoro alkyne dichloridate (TPAC) is a histidine labeling reagent developed by the Chang lab that mimics native post-translational His phosphorylation. The alkyne allows for subsequent reactions or addition of payloads by copper-assisted alkyne-azide cycloaddition (CuAAC) chemistry. TPAC was also demonstrated to covalently modify His-tags, and by clicking on polyarginine tags, enabled protein delivery into live cells.
其他说明
Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation
基本信息
经验(实验)分子式 | C3H3Cl2OPS |
分子量 | 189.00 |
产品性质
质量水平 | 100 |
测定 | ≥95% |
形式 | liquid |
储存温度 | −20℃ |
安全信息
储存分类代码 | 10 - Combustible liquids |
闪点(F) | 175.8 °F |
闪点(C) | 79.9 ℃ |
Sigma-Aldrich