TRAIL, Human, Recombinant, E. coli

产品说明

一般描述

Recombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.

包装

100 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

生化/生理作用

Induces apoptosis in U937 cells at 1 μg/ml within 5 h.

警告

Toxicity: Standard Handling (A)

外形

In 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.

重悬

Following initial thaw, aliquot and freeze

(-70°C).

其他说明

Lin, Y., et al. 2000. Mol. Cell. Biol.20, 6638.
Mitsaides, N., et al. 2000. Cancer Res.60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med.189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol.137, 221.
Pan, G., et al. 1997. Science276, 111.
Pan, G., et al. 1997. Science277, 815.
Sheridan, J.P., et al. 1997. Science277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem.271, 12687.
Wiley, S.R., et al. 1995. Immunity3, 673.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息