产品说明
一般描述
Interleukin-8 (IL-8) is a chemokine produced by macrophages, epithelial cells and endothelial cells. IL-8′s primary function is to recruit neutrophils to phagocytose the antigen which trigger the antigen pattern toll-like receptors. IL-8 can be secreted by any cells with toll-like receptors which are involved in a body’s innate immune response. Once IL-8 is secreted, it becomes an important mediator of immune reaction and inflammatory response. IL-8’s monomer and homodimer forms are both inducers of CXCR1 and CXCR2. IL-8 is also believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.
特异性
Reacts with human IL-8.
No reactivity to IL-1alpha, IL-1beta, IL-2, IL-3, IL4, IL-6, IL-7, IL-10, MIP-1alpha, TNFalpha, GM-CSF and IgG WHO standards by EIA.
免疫原
Recombinant human IL-8.
应用
Research Sub Category
Cytokines & Cytokine Receptors
Anti-Interleukin-8 Antibody is an antibody against Interleukin-8 for use in ELISA & WB.
Western blot: A 1:1000-1:3000 dilution of anti-interleukin-8 (IL-8) detected recombinant human IL-8.
ELISA: A recommended dilution range of 1:100-1:1000 of anti-interleukin-8 (IL-8) was used on recombinant IL-8.
Final working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
质量
Routinely evaluated by western blot on recombinant human IL-8.
目标描述
11 kDa
外形
Liquid in PBS, no preservatives.
Format: Purified
Protein A purified
储存及稳定性
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | ELISA: suitable western blot: suitable |
同位素/亚型 | IgG |
NCBI登记号 | NM_000584.2 |
UniProt登记号 | P10145 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich