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Anti-Amyloid β Antibody, aa1-14 h β-amyloid

Anti-Amyloid β Antibody, aa1-14 h β-amyloid

品牌
Sigma-Aldrich
货号
AB1510
规格纯度
serum, Chemicon®
参考价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Amyloid β Antibody, aa1-14 h β-amyloid
Beta-APP, A-beta
产品介绍:

产品说明

特异性

Beta amyloid. Sequence is contained in the Amyloid beta-A4 protein amino acids 672-685 of human APP. The sequence is identical in the following other related proteins:

Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57).

100% homology in human, pig, sheep, rabbit, bovine, 78% identities (11/14), with 12/14 positives (85%) in rat and mouse beta amyloid containing proteins.

免疫原

Epitope: aa1-14 h beta-amyloid
Synthetic peptide that corresponds to the first 14 amino acids of the N-terminal sequence of beta-amyloid. {DAEFRHDSGYEVHH}

应用

Anti-Amyloid Antibody, β, aa1-14 h β-amyloid detects level of Amyloid & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Immunohistochemistry on formic acid treated histological sections. Suggested working dilution is >1:200. AB1510 will detect both cerebrovascular and core amyloid. Formic acid pretreatment (Vinters et al., 1988) involves deparaffinizing sections, follwed by incubation in a 99% formic acid solution (10-20 min), a tap water rinse (10 min), 0.3% H202 in tris-buffered saline, then 3.0% NGS (30 min) followed by primary antibody.

Immunoblotting of formic acid extracts of brain tissue.

ELISA, direct:≥ 1:1000

Optimal working dilutions must be determined by end user.

外形

Rabbit serum with 0.01% thimerosal.

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式serum
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman
manufacturer/tradenameChemicon®
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NM_000484.2
NM_201413.1
NM_201414.1
UniProt登记号P05067
运输dry ice
Gene Informationhuman ... APP(351)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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