产品说明
特异性
Recognizes phosphorylated Serine133 in cAMP response element binding protein (CREB). By immunoblotting the antibody shows a 5-10 fold increase in staining of a 43 kDa protein after treatment of cells with agents that increase intracellular cAMP. The antibody also recognizes phosphorylated ATF-1 due to a common epitope. The antibody has been preabsorbed with unphosphorylated peptide and will prove to be useful for the investigation of CREB phosphorylation.
免疫原
Epitope: pSer133
Phosphopeptide conjugated to KLH.
应用
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
RNA Binding Protein (RBP)
Anti-CREB Antibody, pSer133 is a Rabbit Polyclonal Antibody for detection of CREB also known as CREB-1, cAMP-response Element-binding Protein-1 & has been validated in WB.
Immunoblotting: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
外形
Rabbit serum. Liquid. The antibody has been preabsorbed with unphosphorylated peptide. Contains 0.01% sodium azide.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | serum |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | rat, mouse, human, monkey |
manufacturer/tradename | Chemicon® |
technique(s) | western blot: suitable |
NCBI登记号 | NM_004379.2 NM_134442.2 |
UniProt登记号 | P16220 |
运输 | wet ice |
Gene Information | human ... CREB1(1385) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich