产品说明

一般描述

Anti-G_qα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies.
Protein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunit proteins.
Recognizes the ~42 kDa G_qα- and the ~43 kDa G₁₁α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family.

免疫原

a synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat G_qα- and G₁₁α-subunits

包装

50 μL in Plastic ampoule

应用

Immunoblotting (1:1000)

Neutralization Studies (see comments)

警告

Toxicity: Standard Handling (A)

其他说明

The antibody recognizes both G_qα and G₁₁α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution.
Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409.
Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707.
Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息