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Interleukin-21 from mouse

品牌
Sigma-Aldrich
货号
I4032
规格纯度
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
参考价格
5033.02 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Interleukin-21 from mouse
IL-21
产品介绍:

产品说明

生化/生理作用

IL-21 (interleukin-21) belongs to the IL-2 cytokine family. It is secreted by CD4+ T, natural killer (NK) and Th17 cells. IL-21 associates with IL-21 receptor and participates in B-cell proliferation, differentiation as well as apoptosis. It also promotes the cytotoxic activity of CD8+ T cells and natural killer cells.IL-21 plays a crucial role in the differentiation of follicular helper T cells. It also exhibits antitumor activity. It is also involved in the activation of JAK-STAT (Janus kinase - signal transducer and activator of transcription), PI3K (phosphatidylinositol 3-kinase) and MAPK (mitogen activated protein kinase) pathways.
IL-21 and its receptor have important roles in T and B cell proliferation and natural killer cell maturation. Human and mouse IL-21 share 57% amino acid identity.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

分析说明

The biological activity is measured by its ability to induce proliferation of human N1186 T cells.

基本信息

MDL编号MFCD03703112
NACRESNA.32

产品性质

生物来源mouse
重组expressed in E. coli
测定≥97% (SDS-PAGE)
形式lyophilized powder
效能40-120 ng/mL ED50
分子量predicted mol wt ~14.4 kDa
包装pkg of 10 μg
储存条件avoid repeated freeze/thaw cycles
technique(s)cell culture | mammalian: suitable
杂质 endotoxin, tested
UniProt登记号Q9ES17
储存温度−20℃
Gene Informationmouse ... Il21(60505)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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