Ubiquitin Aldehyde-Calbiochem

产品说明

一般描述

Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover. Useful for stabilizing endogenous or in vitro synthesized ubiquitin-protein conjugates. May also be used to enhance or decrease the rates of ubiquitin-dependent degradation.
Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover. Useful for stabilizing endogenous or in vitro synthesized ubiquitin-protein conjugates. May also be used to enhance or decrease rates of ubiquitin-dependent degradation.

包装

50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

生化/生理作用

Primary Target
multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover
Product does not compete with ATP.
Shown to inhibit the activity of Isopeptidase T (Cat. No. 419700) and Ubiquitin C-Terminal Hydrolase (Cat. No. 662090)
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

外形

In 150 mM HCL.

重悬

Following reconstitution, aliquot and freeze (-20°C).

其他说明

Melandri, F., et al. 1996. Biochemistry 35, 12893.
Shaeffer, J.R. and Cohen, R.E. 1996. Biochemistry 35, 10886.
Pickart, C.M. and Rose, I.A. 1986. J. Biol. Chem. 261, 10210.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息