产品说明
一般描述
A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. Also induces apoptosis in chronic lymphocytic leukemia (CLL) cells.
包装
10 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Antileukemic and immunosuppressive activity
警告
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
其他说明
Bellosillo, B., et al. 1997. Blood 89, 3378; Bryson, H.M., and Sorkin, E.M. 1993. Drugs 46, 872.
Robertson, L.E., et al. 1993. Blood81, 143.
Carson, D.A., et al. 1988. Adv. Enzyme Regul. 27, 395.
Carson, D.A., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 2232.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C10H12ClN5O3 |
| 分子量 | 285.69 |
| MDL编号 | MFCD00153939 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | white |
| 溶解性 | DMSO: 5 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
| InChI | 1S/C10H12ClN5O3/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/m0/s1 |
| InChI key | PTOAARAWEBMLNO-KVQBGUIXSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H301 - H341 - H361fd - H372 |
| 预防措施声明 | P201 - P202 - P260 - P264 - P270 - P301 + P310 |
| 危险分类 | Acute Tox. 3 Oral - Muta. 2 - Repr. 2 - STOT RE 1 |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
