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4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride

品牌
Sigma-Aldrich
CAS
1375960-13-6
货号
914231
包装型号
规格纯度
≥95%
参考价格
3303.46 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
1375960-13-6
4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride
SFABP
Sulfonyl fluoride activity-based probe
DAS1
产品介绍:

产品说明

应用

4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride is an alkyne-functionalized sulfonyl fluoride activity-based probe (SFABP). Sulfonyl fluorides covalently modify reactive serines in addition to threonine, lysine, tyrosine, cysteine, and histidine residues in a context-specific manner. Activity-based probes are useful for the targeting, isolation, and identification of proteins. Furtermore, the alkyne handle on SFABP enables click chemistry-based incorpoation of azide tags, such as fluorophores or biotins, for visualization or enrichment and detection, respectively.

其他说明

Unbiased Mass Spectrometry Elucidation of the Targets and Mechanisms of Activity-Based Probes: A Case Study Involving Sulfonyl Fluorides

Sulfonyl fluorides as privileged warheads in chemical biology

Chemical Proteomics with Sulfonyl Fluoride Probes Reveals Selective Labeling of Functional Tyrosines in Glutathione Transferase

Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases

Europium-Labeled Activity-Based Probe through Click Chemistry: Absolute Serine Protease Quantification Using 153Eu Isotope Dilution ICP/MS

基本信息

经验(实验)分子式C14H16FNO3S
分子量297.35

产品性质

质量水平100
测定≥95%
形式powder
储存温度−20℃

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids

Sigma-Aldrich

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