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位置:首页 > 品牌 > Sigma-Aldrich > Angiotensin Converting Enzyme-2, His·Tag®, Human, Recombinant, NSO Cells

Angiotensin Converting Enzyme-2, His·Tag®, Human, Recombinant, NSO Cells

品牌
Sigma-Aldrich
货号
176872
包装型号
规格纯度
参考价格
7434.04 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Angiotensin Converting Enzyme-2, His·Tag®, Human, Recombinant, NSO Cells
ACE Homolog, ACEH, ACE-2
产品介绍:

产品说明

一般描述

Recombinant, human ACE-2 ectodomain (amino acids 1-740) fused at the C-terminus to a His•Tag sequence and expressed in NSO cells. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and plays an important role in regulating cardiovascular and renal functions. Native ACE-2 is an integral membrane zinc metalloprotease whose activity is inhibited by EDTA. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing conditions.
Recombinant, human ACE-2 ectodomain (amino acids 1-740) fused at the C-terminus to a His•Tag sequence and expressed in NSO cells. Native ACE-2 is an integral membrane zinc metalloprotease that can be inhibited by EDTA. ACE-2 cleaves angiotensins I and II. Plays an important role in regulating cardiovascular and renal functions. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing condition.

包装

10 μg in Glass bottle
Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

单位定义

One unit is defined as the amount of enzyme that will cleave 1 nmol MCA-YVADAPK(DNP)-OH per min at 25°C, pH 7.5.

重悬

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Tikellis, C., et al. 2003. Hypertension41, 390.
Tipnis, S.R., et al. 2000. J. Biol. Chem.275, 33238.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

质量水平100
重组expressed in NSO cells
测定≥90% (SDS-PAGE)
形式liquid
specific activity≥0.8 units/μg protein
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
avoid repeated freeze/thaw cycles
杂质≤1.0 EU/μg Endotoxins (EU/μg ACE-2)
运输wet ice
储存温度−70℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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