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Anti-Amyloid Precursor Protein Antibody, a.a. 44-63

品牌
Sigma-Aldrich
货号
AB1593
规格纯度
serum, Chemicon®
参考价格
3339.52 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Amyloid Precursor Protein Antibody, a.a. 44-63
APP
产品介绍:

产品说明

特异性

Recognizes amyloid precursor protein (APP). In Alzheimer′s disease, this protein is broken down and releases the 12 amino acid b-amyloid protein that is found in senile plaques and vessels.

The amyloid precursor protein is the subject of intensive investigations to determine how this protein is broken down abnormally in Alzheimer′s disease to give rise to the b-amyloid protein which is present in senile plaques and vessels. This antiserum has been shown to be immunoreactive to the immunizing peptide by ELISA. The antiserum will immunolabel dystrophic neurites in senile plaques in both formalin-fixed paraffin sections and paraformaldehyde fixed frozen sections from Alzheimer′s brain.

This antiserum should be a valuable tool for scientist and neuropathologists who study the role of amyloid in Alzheimer′s′s disease.

免疫原

Peptide to the N-terminal region (amino acids 44-63) of the APP protein.
Epitope: a.a. 44-63

应用

Anti-Amyloid Precursor Protein Antibody, a.a. 44-63 is an antibody against Amyloid Precursor Protein for use in ELISA, IF, WB, IH, IH(P).
Research Category
Neuroscience
Immunoblotting: 1:1,000

Immunofluorescence

Immunohistochemistry

Formalin fixed paraffin embedded tissue:1:50-1:100

4% paraformaldehyde fixed frozen sections: 1:2,500-1:5,000

ELISA: 1:1,500 against immunogen peptide

Optimal working dilutions must be determined by end user.
Research Sub Category
Neurodegenerative Diseases

外形

Goat antiserum. Liquid with 0.1% Sodium Azide

储存及稳定性

Store at -20ºC in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源goat
抗体形式serum
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman
manufacturer/tradenameChemicon®
technique(s)ELISA: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
NCBI登记号NM_000484.2
NM_201413.1
NM_201414.1
UniProt登记号P05067
运输dry ice
Gene Informationhuman ... APP(351)

Sigma-Aldrich

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