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位置:首页 > 品牌 > Sigma-Aldrich > Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2

Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2

品牌
Sigma-Aldrich
货号
MABS45
规格纯度
clone CPTC-ANXA1-2, from mouse
参考价格
4848.93 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2
annexin A1, chromobindin-9, annexin I (lipocortin I), Lipocortin I, calpactin-2, Calpactin II, annexin-1, Phospholipase A2 inhibitory protein, Annexin I, Calpactin-2, Annexin-13, Chromobindin-9
产品介绍:

产品说明

一般描述

Annexin A1 (ANXA1) is a calcium and phospholipid binding protein almost entirely restricted to microglia in the CNS. During the peripheral inflammatory response, Annexin A1 is instrumental in the phagocytosis of apoptotic leukocytes. Annexin A1 restores the ability of microglia to differentiate between apoptotic and non-apoptotic cells during inflammatory activation. Current research is geared towards using Annexin A1 as a therapeutic target in neuroinflammation. Annexin A1 has also been shown to be influential in cancer development and proliferation.

免疫原

Full length recombinant protein corresponding to human Annexin A1.

Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program

应用

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (http://antibodies.cancer.gov/antibodies/detail/CPTC-ANXA1-2)


Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2 is validated for use in WB, IH for the detection of Annexin A1.
Research Category
Signaling

质量

Evaluated by Western Blot in K562 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Annexin A1 on 10 µg of K562 cell lysate.

目标描述

~ 39 kDa observed

外形

Format: Purified
Protein G
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
K562 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆CPTC-ANXA1-2, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG2aκ
NCBI登记号NP_000691
UniProt登记号P04083
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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