产品说明
一般描述
Aquaporins (AQPs) are a family of channel proteins that allow water or very small solutes to pass, functioning in tissues where the rapid and regulated transport of fluid is necessary, such as the kidney, lung, and salivary glands. Aquaporin 5 is considered to play an important role in water movement across the plasma membrane in salivary fluid secretion and corneal/lens lubrication and is a focus of studies illucidating bechanisms underlying diabetic xerostomia.
特异性
Aquaporin 5 (AQP5). By Western blot the antibody reacts with a band at ~ 24 kDa on rat submaxillary gland lysate.
免疫原
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat Aquaporin 5.
Epitope: Cytoplasmic domain
应用
This Anti-Aquaporin 5 (AQP5) Antibody is validated for use in WB for the detection of Aquaporin 5 (AQP5).
Research Category
Neuroscience
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Aquaporin 5 in rat lung and mouse trachea tissue.
Immunohistochemistry Analysis: A representative lot from independent laboratories detected Aquaporin 5 in various paraformaldehyde fixed tissues (see references).
Research Sub Category
Developmental Signaling
质量
Evaluated by Western Blotting in rat salivary gland tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected Aquaporin 5 in 10 µg of rat salivary gland tissue lysate.
目标描述
~28 kDa observed
外形
ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
储存及稳定性
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
分析说明
Control
Tested on Rat Salivary Gland Lysate
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse, rat |
manufacturer/tradename | Chemicon® |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
NCBI登记号 | NP_036911 |
UniProt登记号 | P47864 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich