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Anti-CXCR4 antibody produced in chicken

品牌
Sigma-Aldrich
货号
GW21075
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-CXCR4 antibody produced in chicken
Anti-C-X-C chemokine receptor type 4
产品介绍:

产品说明

免疫原

Recombinant chemokine (C-X-C motif) receptor 4 isoform b
Immunogen Sequence: GI # 4503175, sequence 6-41

应用

Anti-CXCR4 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

C-X-C chemokine receptor type 4 (CXCR-4) is a protein encoded by the CXCR4 gene in humans. It is expressed in various cell types and the mechanisms involved in the regulation of its expression are still unknown. CXCR4 is a cofactor for fusion and entry of T cell-tropic strains of HIV-1. It is a chemokine receptor that is overexpressed in certain cancer types and involved in migration toward distant organs. CXCR4 is associated with various functions such as embryo organogenesis, immunological functions and T lymphocyte trafficking. High CXCR4 expression can be helpful in predicting clear-cell renal cell carcinoma (ccRCC). It plays a vital role in modulating cell trafficking in hematopoietic stem cells and clonal B cells. CXCR4 plays an important role in biological processes, as well as in tumorigenesis and the progression of cancer, especially breast cancer. It is an efficient prognostic factor for breast cancer.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01092337
NACRESNA.41

产品性质

生物来源chicken
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivitymouse, rat, human
manufacturer/tradenameGenway 15-288-21075
technique(s)western blot: suitable
NCBI登记号NP_003458.1
UniProt登记号P61073
运输wet ice
储存温度−20℃
Gene Informationhuman ... CXCR4(7852)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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