Anti-Endoglin antibody produced in chicken

产品说明

免疫原

Recombinant endoglin
Immunogen Sequence: GI # 4557555, sequence 341-470

应用

Anti-Endoglin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Endoglin is a type I transmembrane glycoprotein located on cell surfaces belonging to the transforming growth factor β superfamily. It is commonly referred to as CD105, END, HHT1 and ORW1. It is a part of the TGF β receptor complex, which plays an important role in angiogenesis. CD105 expression correlates with prognosis for several cancers and plays an important role in the pancreatic cancer microenvironment. Tumoral CD105 acts as an independent predictive marker for death risk. Mutation in endoglin causes a vascular defect, hereditary hemorrhagic telangiectasia (HHT1).

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息