产品说明
一般描述
Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
特异性
Reactivity with other species has not been determined.
Cat. # AB2233 recognizes Galanin
免疫原
Synthetic Linear Peptide
应用
Research Sub Category
Neurochemistry & Neurotrophins
Research Category
Neuroscience
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
质量
Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
目标描述
13.3 kDa
外形
Serum with 0.05% NaN3
储存及稳定性
Maintain at -20°C for up to 1 year from date of receipt.
分析说明
Control
Rat Cerebellum Tissue
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | serum |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | rat |
species reactivity (predicted by homology) | mouse, human, boar |
technique(s) | immunohistochemistry: suitable (paraffin) |
NCBI登记号 | NP_057057 |
UniProt登记号 | P22466 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
Sigma-Aldrich