Anti-Interleukin-17a antibody produced in chicken

产品说明

一般描述

Interleukin-17a (IL-17A) is a member of the six member pro-inflammatory cytokine family called IL-17. The members are designated from IL-17A to IL-17F. IL-17A is synthesized by TH17 cells belonging to the CD4⁺ and CD8⁺ lineage. This gene is localized to human chromosome 6p12.1.

免疫原

Recombinant interleukin 17A
Immunogen Sequence: GI # 4504651, sequence 20-155

应用

Anti-Interleukin-17a antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Interleukin-17A is a proinflammatory cytokine produced mainly by CD4⁺ T-lymphocytes and plays a critical role in inflammation. Chronic inflammation is a pathological feature of cancer. It may play an important role in tumor cell growth and progression. IL-17 levels might be useful for diagnostic and prognostic test for lung cancer patients with malignant pleural effusion (MPE). Cells producing IL-17 may act as a useful biomarker for the prognosis of sarcoidosis and play a role in the spontaneous recovery typical of patients with Löfgren′s syndrome.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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