产品说明
一般描述
Lysosome-associated membrane protein 1 (LAMP-1) is a highly glycosolated, single-pass type 1 membrane protein belonging to the lysosome- associated membrane protein family; a group of proteins that make up the majority of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-1 functions to traffic carbohydrate ligands to selectins. It is also thought to play a role in tumor cell metastasis.
免疫原
NIH/3T3 plasma membrane fraction of mouse LAMP-1.
应用
Research Sub Category
Apoptosis - Additional
Tumor Markers
Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Chen, 1985).
Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Chen, 1985).
Detect LAMP-1 (CD107a) using this Anti-LAMP-1 (CD107a) Antibody, clone 1D4B validated for use in WB, IP, IC, IH, FC.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 1:50,000 dilution of this antibody detected LAMP-1 in 10 µg of NIH/3T3 cell lysate.
目标描述
~ 100 kDa observed. The calculated molecular weight of this protein is 44 kDa The protein is heavily glycosolated and therefore its molecular weight is typically noted from 95-115 kDa
外形
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
NIH/3T3 cell lysate
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | rat |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 1D4B, monoclonal |
species reactivity | mouse |
technique(s) | flow cytometry: suitable immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
同位素/亚型 | IgG2aκ |
NCBI登记号 | NP_034814 |
UniProt登记号 | P11438 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich