产品说明
一般描述
LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
免疫原
GST-tagged recombinant protein corresponding to mouse LYAR.
应用
Research Sub Category
Immunoglobulins & Immunology
Pluripotent & Early Differentiation
Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.
质量
Evaluated by Western Blot in mouse embryonic stem cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.
目标描述
~48 kDa observed
外形
Affinity purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
technique(s) | western blot: suitable |
NCBI登记号 | NP_079557 |
UniProt登记号 | Q08288 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich