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Anti-Pleiotrophin Antibody, clone 3B10

品牌
Sigma-Aldrich
货号
MABC42
规格纯度
clone 3B10, from mouse
参考价格
6190.47 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Pleiotrophin Antibody, clone 3B10
pleiotrophin, neurite growth-promoting factor 1, Heparin-binding brain mitogen, heparin binding growth factor 8, Heparin-binding growth-associated molecule, heparin affin regulatory protein, Heparin-binding neurite outgrowth-promoting factor 1, pleiotrop
产品介绍:

产品说明

一般描述

Pleiotrophin (PTN) also called Neurite Growth-promoting Factor 1 (NEGF1) or HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN plays an important role in development processess and promotion of neurite extension. During embryonic development, pleiotrophin is expressed in the central and peripheral nervous system, lung, kidney, gut and bone. Pleiotrophin is also expressed by several tumor cells and is thought to be involved in tumor angiogenesis. PTN initiates an angiogenic switch in different cancer models and acts as an angiogenic factor. PTN does this through an interaction with endothelial cells to initiate proliferation, migration, and tube formation.

免疫原

Recombinant protein corresponding to chicken Pleiotrophin.

应用

Research Sub Category
Apoptosis - Additional

Developmental Neuroscience
Research Category
Apoptosis & Cancer
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Pleiotrophin in papillary squamous cell carcinoma tissue.
This Anti-Pleiotrophin Antibody, clone 3B10 is validated for use in IH, WB for the detection of Pleiotrophin.

质量

Evaluated by Western Blot in human placenta tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Pleiotrophin in 10 µg of human placenta tissue lysate.

目标描述

~20 kDa observed

联系

Replaces: MABD179

外形

Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing PBS without 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Human placenta tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆3B10, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号XP_416358
UniProt登记号P32760
运输wet ice
Gene Informationhuman ... PTN(5764)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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