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Anti-PORCN Antibody, clone 15G12.1

品牌
Sigma-Aldrich
货号
MABS21
规格纯度
clone 15G12.1, from mouse
参考价格
4848.93 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PORCN Antibody, clone 15G12.1
Probable protein-cysteine N-palmitoyltransferase porcupine, Protein MG61
产品介绍:

产品说明

一般描述

PORCN is a multi-pass endoplasmic reticulum protein involved in the processing of wingless and other Wnt proteins that facilitate their secretion from Wnt-producing cells. Studies have shown mutations in the genes that encode for PORCN cause a pleiotropic X-linked dominant disorder, focal dermal hypolasia (FDH, also known as Goltz syndrome). Skeletal abnormalities such as syndactyly, ectordactyly, and brachydactyly, and some cases of osteopathia striata have also been attibuted to PORCN abnormalities.

免疫原

Linear peptide corresponding to human PORCN.

应用

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PORCN in HeLa and A431 cells.
Research Category
Signaling
Anti-PORCN Antibody, clone 15G12.1 is an antibody against PORCN for use in WB & IC.
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected PORCN in 10 µg of mouse brain tissue lysate.

目标描述

~62 kDa observed.
Calculated molecular weight of 52 kDa The actual MW should be observed at ~45-65 kDa Helical membrane protein migration on SDS-PAGE may not exactly correlate with the calculated molecular weights (PNAS, 2009, 106:1760-1765).

外形

Purified by Ion-Exchange Chromatography
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆15G12.1, monoclonal
species reactivitymouse, rat, human
technique(s)immunocytochemistry: suitable
western blot: suitable
同位素/亚型IgMκ
NCBI登记号NP_073736
UniProt登记号Q9H237
运输wet ice

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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