Anti-PTPRC antibody produced in chicken

产品说明

免疫原

Immunogen Sequence: GI # 18641347, sequence 482-552
Recombinant protein tyrosine phosphatase, receptor type, C isoform 1

应用

Anti-PTPRC antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Protein tyrosine phosphatase, receptor type, C is an enzyme encoded by the PTPRC gene in humans. It is also known as CD45 antigen (CD stands for cluster of differentiation) and is originally called leukocyte common antigen (LCA). PTPRC acts as a binding receptor for galectin-3 and helps in inducing apoptosis of Jurkat cells. It plays a novel role on innate immune cells in promoting lymphopenia-induced T cell proliferation. The leukocyte-specific tyrosine phosphatase impacts T cell development and activation by modulating TCR signaling.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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