APN-COCI

产品名称：

APN-COCI
4-(cyanoethynyl)benzoyl chloride

产品介绍：

产品说明

应用

APN-COCl is a bifunctional reagent appropriate for the introduction of APN function.

包装

50 mg in glass bottle

其他说明

The coupling between an amine and APN-COCl should be performed in dry organic solvents (e.g. THF) in the presence of a base (e.g. TEA). The resulting conjugate can be readily coupled with thiol-containing biomolecules using the following protocol:

Dissolve the protein in the appropriate buffer with pH 6.5-9.0 (e.g. PBS) at 1-10 mg/mL concentration.
Apply the appropriate amount of the stock solution of the APN-labeled molecule (1-5 molar eq. per free cysteine residue).
Incubate at room temperature for 2 hours.

If necessary, purify the protein conjugate using size exclusion chromatography or ultrafiltration.

基本信息

经验(实验)分子式	C₁₀H₄ClNO
分子量	189.60
PubChem化学物质编号	329768747

产品性质

形式	powder
质量水平	100
reaction suitability	reagent type: cross-linking reagent
储存温度	2-8℃
SMILES string	N#CC#CC1=CC=C(C(Cl)=O)C=C1
InChI	1S/C10H4ClNO/c11-10(13)9-5-3-8(4-6-9)2-1-7-12/h3-6H
InChI key	OWNJCJKKKZXTIX-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H314
预防措施声明	P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable