产品说明
应用
This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.
Bromo-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
经验(实验)分子式 | C9H17BrO5 |
分子量 | 285.13 |
MDL编号 | MFCD22574820 |
NACRES | NA.22 |
产品性质
形式 | liquid |
储存温度 | −20℃ |
SMILES string | BrCCOCCOCCOCCC(O)=O BrCCOCCOCCOCCC(O)=O |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Sigma-Aldrich