产品说明
一般描述
Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).
A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.
包装
10 mg in Plastic ampoule
生化/生理作用
Primary Target
Substrate for the determination of cathepsin D activity
Product does not compete with ATP.
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl
其他说明
Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C49H55N9O7 · xHCl |
| 分子量 | 882.02 (free base basis) |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated protect from light |
| 颜色 | white |
| 溶解性 | DMSO: 5 mg/mL |
| 荧光 | λex ~345 nm λem ~425 nm |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
