产品说明
一般描述
A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 70 nM).
包装
10 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Primary Target
PDE 3
Product does not compete with ATP.
Reversible: no
Target IC50: 70 nM against PDE III
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
其他说明
Verghese, M.W., et al. 1995. J. Pharmacol. Exp. Ther. 272, 1313.
Christensen, S.B., and Trophy, T.J. 1994. Ann. Rep. Med. Chem. 29, 185.
Tang, K.M., et al. 1994. Eur. J. Pharmacol. 268, 105.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C20H26N2O3 |
分子量 | 342.43 |
MDL编号 | MFCD00673958 |
产品性质
质量水平 | 100 |
测定 | ≥98% (TLC) |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze |
颜色 | white |
溶解性 | DMSO: 5 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
InChI | 1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23) |
InChI key | UIAYVIIHMORPSJ-UHFFFAOYSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich