E-Selectin, Human, Recombinant, CHO Cells

产品说明

一般描述

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

包装

50 μg in Plastic ampoule

生化/生理作用

Shown to bind to E-selectin ligands on U937 cells.

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from Dulbecco′s PBS with stabilizer.

重悬

Reconstitute to 1 mg/ml with sterile H₂O.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息