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ERO1 Inhibitor I, Erodoxin-Calbiochem

品牌
Sigma-Aldrich
货号
328500
规格纯度
The ERO1 Inhibitor I, Erodoxin controls the biological activity of ERO1.
参考价格
3543.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
ERO1 Inhibitor I, Erodoxin-Calbiochem
1-Bromo-5-methoxy-2,4-dinitrobenzene, Endoplasmic Reticulum Oxidase 1 Inhibitor
产品介绍:

产品说明

一般描述

A cell-permeable dinitrobromobenzene compound that acts as a selective inhibitor of yeast Endoplasmic Reticulum Oxidase 1 (ERO1), but has somewhat weaker activity against mouse ERO1α (IC50 = 400 µM). Predicted to form thiol adducts and inhibits ERO1-dependent oxidation of thioredoxin-1 (Trx1) activity in vitro. Shown to cluster with genes involved in protein folding, glycosylation and cell wall biosynthesis, and delay carboxypeptidase Y (CPY) processing to the vacuolar form in wt-yeast cells.

包装

25 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze(-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Costanzo, M., et al. 2010. Science327, 425.
Blais, J.D., et al. 2010. J. Biol. Chem.285, 20993.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C7H5BrN2O5
分子量277.03
MDL编号MFCD00624873

产品性质

质量水平100
测定≥99% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 100 mg/mL (Use only fresh DMSO)
运输wet ice
储存温度2-8℃
SMILES stringBrC(C=C(C([N+]([O-])=O)=C1)OC)=C1[N+]([O-])=O

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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