Fmoc-<sc>L</sc>-photo-leucine

产品名称：

1360651-24-6
Fmoc-L-photo-leucine
Photo-crosslinking amino acid
(S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-3-(3-methyl-3H-diazirin-3-yl)propanoic acid
Photoprobe building block
(S)-2-(Fmoc-amino)-3-(3H-diazirin-3-yl)butanoic acid
Photo-Leu

产品介绍：

产品说明

应用

Fmoc-L-Photo-Leucine is a diazirine-containing, Fmoc-protected leucine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907278.

其他说明

Synthesis of a polymyxin derivative for photolabeling studies in the gram-negative bacterium Escherichia coli

Developing diazirine-based chemical probes to identify histone modification ′readers′ and ′erasers′

Protein-Polymer Conjugation via Ligand Affinity and Photoactivation of Glutathione S-Transferase

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

基本信息

经验(实验)分子式	C₂₀H₁₉N₃O₄
分子量	365.38

产品性质

测定	≥98%
形式	powder
reaction suitability	reaction type: Fmoc solid-phase peptide synthesis
application(s)	peptide synthesis
官能团	Fmoc
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable