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Granulocyte Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli

品牌
Sigma-Aldrich
货号
234374
规格纯度
Granulocyte Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli, is a pleiotropic cytokine that can stimulate the proliferation, maturation, and function of hematopoietic cells.
参考价格
7547.78 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
Granulocyte Macrophage Colony-Stimulating Factor, Mouse, Recombinant, E. coli
rmGM-CSF
产品介绍:

产品说明

一般描述

Recombinant, mouse granulocyte macrophage colony-stimulating factor expressed in E. coli. Pleiotropic cytokine that can stimulate the proliferation, maturation, and function of hematopoietic cells. Reported to improve the response rate to antibiotic therapy in cancer subjects. Activates JAK2 in a variety of cells.
Recombinant, mouse granulocyte macrophage colony-stimulating factor expressed in E. coli. Pleiotropic cytokine that stimulates the proliferation, maturation, and function of hematopoietic cells. Reported to improve the response rate to antibiotic therapy in cancer subjects. Activates JAK2 in a variety of cells. Target cells include macrophages, granulocytes, and eosinophils. GM-CSF is produced by many cell types, including endothelial cells, fibroblasts, and T-lymphocytes. It can be extracted from most tissues in concentrations exceeding that of serum levels. While many cells produce GM-CSF constitutively, levels of this lymphokine increase rapidly in response to endotoxin, phorbol esters, and certain antigens.

包装

10 μg in Plastic ampoule

生化/生理作用

ED₅₀ = 100-300 pg/ml as measured in a cell proliferation assay using a factor-dependent cell line, DA-3

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from sterile-filtered PBS containing 50 µg BSA/µg GM-CSF.

重悬

Reconstitute to a concentration of ≥10 µg/ml with sterile PBS containing ≥0.1% HSA or BSA.
Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for 3 months at 4°C.

其他说明

Anaissie, E.J., et al. 1996. Am. J. Med. 100, 15.
Watanabe, S., et al. 1996. J. Biol. Chem.271, 12681.
Moore, M.A. 1991. Annu. Rev. Immunol. 9, 159.
Nicola, N.A. 1989. Annu. Rev. Biochem. 58, 45.
Gough, N.M., et al. 1985. EMBO J. 4, 645.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

质量水平100
重组expressed in E. coli
测定>97% (SDS-PAGE)
形式lyophilized
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
杂质≤1.0 EU/μg Endotoxin (EU/μg GM-CSF)
运输ambient
储存温度−70℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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