Histone Acetyltransferase Activator, CTB-CAS 451491-47-7-Calbiochem

品牌

Sigma-Aldrich

CAS

451491-47-7

货号

382120

包装型号

25 MG, The Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure ap

规格纯度

The Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of Histone. This small molecule/inhibitor is primarily used for Cell Structure applications.

参考价格

2683.2 元 *本价格含增值税费

促销

数量

产品名称：

451491-47-7
Histone Acetyltransferase Activator, CTB-CAS 451491-47-7-Calbiochem
EP300 Activator, E1A binding protein 300 Activator, N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-ethoxybenzamide
N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-ethoxybenzamide, EP300 Activator, E1A binding protein 300 Activator

产品介绍：

产品说明

一般描述

A benzamide compound that activates the histone acetyltransferase (HAT) activity of p300/EP300/E1A binding protein 300 in a dose-dependent manner (~6-fold of basal HAT activity of recombinant human p300 toward purified HeLa core histones in the presence of 250 µM CTB). SERS spectrum indicates that CTB interacts with p300 preferentially via the amide groups of the α-helix and β-sheets, resulting in altered enzyme conformation, which presumably accounts for the increased enzymatic activity.

包装

25 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Mantelingu, K., et al. 2007. J. Phys. Chem. B111, 4527.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₆H₁₃ClF₃NO₂
分子量	343.73

产品性质

质量水平	100
测定	≥90% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	off-white
溶解性	ethanol: 5 mg/mL
运输	ambient
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2