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Honokiol-CAS 35354-74-6-Calbiochem

品牌
Sigma-Aldrich
CAS
35354-74-6
货号
384620
规格纯度
A biphenyl neolignan and an active principle of Magnolia extract that displays anti-angiogenic, anti-tumor and anxiolytic properties.
参考价格
1977.69 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
35354-74-6
Honokiol-CAS 35354-74-6-Calbiochem
5,3'-Diallyl-2,4'-dihydroxydiphenyl, VEGFR Tyrosine Kinase Inhibitor XIX, VEGFR2 Kinase Inhibitor XV
产品介绍:

产品说明

一般描述

A biphenyl neolignan and an active principle of Magnolia extract that displays anti-angiogenic, anti-tumor and anxiolytic properties. Shown to induce apoptosis and preferentially inhibit the growth of primary human endothelial cells over fibroblasts by blocking VEGFR2 autophosphorylation and subsequent rac activation. Also blocks the in vivo growth of SVR angiosarcoma in nude mice.
The active principle of Magnolia extracts that exhibits anti-angiogenic, anti-tumor, anxiolytic, and chemoprotective properties. Shown to induce apoptosis and preferentially inhibit the growth of primary human endothelial cells over fibroblasts by blocking vascular endothelial growth factor receptor 2 (VEGFR2) autophosphorylation and subsequent rac activation. Also shown to block the growth of SVR angiosarcoma in nude mice.

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Anti-angiogenic, anti-tumor and anxiolytic properties

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Bai, X., et al. 2003. J. Biol. Chem.278, 35501.
Yang, S.E., et al. 2002. Biochem. Pharmacol.63, 1641.
Son, H.J., et al. 2000. Planta Med.66, 469.
Maruyama, Y., et al. 1998. J. Nat. Prod.61, 135.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C18H18O2
分子量266.33
MDL编号MFCD00016674

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性DMSO: 10 mg/mL
ethanol: soluble
运输ambient
储存温度2-8℃
InChI1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChI keyFVYXIJYOAGAUQK-UHFFFAOYSA-N

安全信息

象形图GHS05GHS09
警示用语:Danger
危险声明H318 - H411
预防措施声明P273 - P280 - P305 + P351 + P338 - P391 - P501
危险分类Aquatic Chronic 2 - Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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