产品说明
一般描述
A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
包装
10 mg in Glass bottle
Packaged under inert gas
生化/生理作用
Primary Target
Metalloproteases
Cell permeable: no
Reversible: yes
警告
Toxicity: Standard Handling (A)
外形
Supplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
重悬
Following initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
其他说明
Merck Index: 14, 9842.
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab.79, 171.
Taylor, A., et al. 1993. Biochemistry32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr.305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol.36, 75.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C16H24N2O4 · xHCl |
| 分子量 | 308.37 (free base basis) |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | liquid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze avoid repeated freeze/thaw cycles protect from light |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O.[xHCl] |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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