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MIF Antagonist IV, RDR 03785-Calbiochem

品牌
Sigma-Aldrich
货号
475847
规格纯度
The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.
参考价格
2280.37 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
MIF Antagonist IV, RDR 03785-Calbiochem
Macrophage Migration Inhibitory Factor Antagonist IV, 6-(Morpholino(4-(trifluoromethyl)phenyl)methyl)-1,3-benzodioxol-5-ol
产品介绍:

产品说明

一般描述

A cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4 µM, respectively) via direct non-covalent MIF interaction (KD = 24.5 µM). RDR 03758 at 10 µM is shown to completely neutralize the overriding effect of 100 ng/ml MIF on the inhibition of LPS-stimulated TNF production by dexamethasone (Cat. No. 265005) in RAW 264.7 marcophage cultures.

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Ouertatani-Sakouhi, H., et al. 2010. J. Biol. Chem.285, 26581.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C19H18F3NO4
分子量381.35

产品性质

质量水平100
测定≥97% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 cream
溶解性DMSO: 50 mg/mL, clear, colorless
运输ambient
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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