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Milrinone-CAS 78415-72-2-Calbiochem

品牌
Sigma-Aldrich
CAS
78415-72-2
货号
475840
规格纯度
A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 300 nM).
参考价格
4330.43 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
78415-72-2
Milrinone-CAS 78415-72-2-Calbiochem
1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
产品介绍:

产品说明

一般描述

A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III, IC50 = 300 nM). Has positive chronotropic, ionotropic, and vasodilatory effects on the heart.
A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 300 nM). Has positive chronotropic, inotropic, and vasodilatory effects on the heart.

包装

10 mg in Alu drum

生化/生理作用

Cell permeable: yes
Primary Target
PDE 3
Product does not compete with ATP.
Reversible: no
Target IC50: 300 nM against PDE III

警告

Toxicity: Toxic (F)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

其他说明

Bailey, J.M., et al. 1994. Anesthesiology 81, 616.
Wilhelm, D., et al. 1992. J. Cardiovasc. Pharmacol.20, 705.
Lindgren, S.H., et al. 1990. Acta. Phys. Scand.140, 209.
Harrison, S.A., et al. 1986. Mol. Pharmacol.29, 506.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C12H9N3O
分子量211.22
MDL编号MFCD00133539

产品性质

质量水平100
测定≥99% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white
溶解性DMSO: 20 mg/mL
ethanol: 3 mg/mL
运输ambient
储存温度−20℃
InChI1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChI keyPZRHRDRVRGEVNW-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P264 - P270 - P301 + P310 - P405 - P501
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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