NanoFabTx^TM Polymer drug formulation kit

产品说明

一般描述

NanoFabTx^™ formulation kits and lipid mixes enable users to encapsulate a wide variety of therapeutic drug molecules for targeted or extended drug delivery without the need for lengthy trial-and-error optimization. NanoFabTx^™ kits provide an easy to use toolkit for encapsulating a variety of therapeutics in nanoparticles, microparticles, or liposomes. Drug encapsulated particles synthesized with the NanoFabTx^™ kits are suitable for biomedical research applications such as oncology, immuno-oncology, gene delivery and vaccine delivery.

应用

The NanoFabTx^™ Polymer drug formulation kit, PLA, 100-200nm nanoparticles is a ready-to-use nanoformulation kit for nanoparticle synthesis for drug delivery. This kit provides properly selected PLA based formulation materials, and protocols, tested by nanoprecipitation and microfluidic methods, for the facile fabrication of PLA nanoparticles, suitable for pharmaceutical researches and applications.

This kit minimizes laboratory setup with optimized protocols and step-by-step instruction for synthesizing drug-encapsulated nanoparticle-based formulations. Poly(D,L-lactic acid) (PLA) is a biocompatible and biodegradable polymer that has been approved by the FDA for biomedical and pharmaceutical applications. PLA based nanoparticles have been widely used as drug delivery systems for different types of therapeutic molecules, to achieve controlled drug release.
NanoFabTx^™ Polymer drug formulation kit PLA, 100-200nm nanoparticles for nanoparticle synthesis for drug delivery

特点和优势

• Ready-to-use nanoformulation kit for PLA nanoparticles
• Step-by-step protocols developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible nanoparticles
• Optimized to make nanoparticles 100–200 nm nanoprecipitation or microfluidics with low polydispersity
• Based on non-toxic, biodegradable polymers

Comprehensive protocols for two different particle synthesis methods are included:

• A nanoprecipitation protocol to prepare drug-encapsulated nanoparticles in standard laboratory glassware.
• A microfliuidics protocol using commercial platforms or syringe pumps.

The microfluidics protocol uses NanoFabTx^™ device kits (911593), which provide all the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

For more information, please refer to the protocol under the document section of this page.

法律信息

NANOFABTX is a trademark of sigma-aldrich Co. LLC

产品性质

形式	nanoparticles
分子量	PLA
粒径	100-200 nm
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3