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Nimodipine-CAS 66085-59-4-Calbiochem

品牌
Sigma-Aldrich
CAS
66085-59-4
货号
482200
规格纯度
An L-type Ca2+ channel blocker.
参考价格
820 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
66085-59-4
Nimodipine-CAS 66085-59-4-Calbiochem
1,4-Dihydro-2,6-dimethyl-4-(3'-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl-1-methylethyl Ester
产品介绍:

产品说明

一般描述

An L-type Ca2+ channel blocker. Enhances memory in old or brain-damaged animals. Ameliorates experimental diabetic neuropathy in streptozotocin-induced diabetic rats.
An L-type Ca2+ channel blocker. Enhances memory in old or brain-damaged animals. Ameliorates experimental diabetic neuropathy in streptozotocin-induced diabetic rats. Also reported to block TNF-α and LPS-induced iNOS activity (IC50 = 36 pM) in mouse astroglial cells.

包装

25 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Reversible: no
Primary Target
L-type Ca2+ channel blocker
Cell permeable: no
Target IC50: 36 pM blocking TNF-α and LPS-induced iNOS activity in mouse astroglial cells

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Zhu, D., et al. 1999. Life. Sci.65, PL 221.
Marchetti, C. and Usai, C. 1996. Neurosci. Lett. 207, 77.
Kappelle, A.C., et al. 1994. Br. J. Pharmacol.111, 887.
Weiss, J.H., et al. 1994. J. Neurochem. 62, 372.
Kappelle, A.C., et al. 1993. Br. J. Pharmacol.108, 780.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C21H26N2O7
分子量418.44
MDL编号MFCD00153848

产品性质

质量水平100
测定>98% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 25 mg/mL
methanol: soluble
运输ambient
储存温度2-8℃
InChI1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
InChI keyUIAGMCDKSXEBJQ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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