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Propargyl-PEG2-acid

品牌
Sigma-Aldrich
CAS
1859379-85-3
货号
901566
包装型号
规格纯度
参考价格
1526.69 *本价格含增值税费
促销
服务
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数量
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产品名称:
1859379-85-3
Propargyl-PEG2-acid
产品介绍:

产品说明

应用

Propargyl-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains two PEG units to help improve solubility.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C8H12O4
分子量172.18
NACRESNA.22

产品性质

形式liquid
reaction suitabilityreaction type: click chemistry
储存温度−20℃
SMILES stringC#CCOCCOCCC(O)=O

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3

Sigma-Aldrich

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