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位置:首页 > 品牌 > Sigma-Aldrich > PTEN, His-Tag® and S-Tag, Human Recombinant, S. frugiperda

PTEN, His-Tag® and S-Tag, Human Recombinant, S. frugiperda

品牌
Sigma-Aldrich
货号
481409
包装型号
规格纯度
参考价格
7715.05 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
PTEN, His-Tag® and S-Tag, Human Recombinant, S. frugiperda
Phosphatase and Tensin Homolog Deleted on Chromosome 10
产品介绍:

产品说明

一般描述

Full-length, recombinant, human PTEN (GenBank target symbol = PTEN, ACC No. BC_005821) fused at N-terminus to a His•Tag and S•Tag sequences and expressed in S. frugiperda insect cells. PTEN is a tumor suppressor that is frequently found mutated in human cancers. It serves as a lipid phosphatase and negative regulator of the PI-3K/Akt pathway. Absence of functional PTEN results in constitutive activation of Akt and mTOR kinases.

包装

10 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

单位定义

One unit is defined as the amount of enzyme required to liberate 1 nmol phosphate from PIP₃ per min at 37°C.

外形

In 150 mM NaCl, 50 mM Tris-HCl, 5 mM DTT, 1 mM EDTA, 50% glycerol, pH 7.5.

重悬

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Harrington, L.S., et al. 2005. Trends Biochem. Sci.30, 35.
Osaki, M., et al. 2004. Apoptosis9, 667.
Lennon, G., et al. 1996. Genomics33, 151.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

质量水平100
测定≥80% (SDS-PAGE)
形式liquid
specific activity≥75 units/mg protein
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
运输wet ice
储存温度−70℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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