您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > SILuTMProt IGFBP7 Insulin-like growth factor-binding protein 7 human

SILuTMProt IGFBP7 Insulin-like growth factor-binding protein 7 human

品牌
Sigma-Aldrich
货号
MSST0037
规格纯度
recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled
参考价格
9134.92 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
SILuTMProt IGFBP7 Insulin-like growth factor-binding protein 7 human
IGF-bindingprotein7
IGFBP-7
PGI2-stimulating factor
Tumor-derived adhesion factor (TAF)
IBP-7
IGFBP-rP1
MAC25 protein
Prostacyclin-stimulating factor
IGF-binding protein 7
产品介绍:

产品说明

一般描述

IGFBP7 regulates the availability of insulin-like growth factors (IGFs) in tissue, and modulates IGF binding to its receptors. IGFBP7 binds to IGF with high affinity. Several studies have shown the involvement of IGFBP7 in Acute Kidney Injury (AKI), where its levels can predict patients at risk for developing AKI. When combined with TIMP-2, the accuracy of AKI risk prediction is further increased. Urinary [TIMP-2]×[IGFBP7] test sufficiently detects patients with risk of AKI after major non-cardiac surgery. In addition, Urinary [TIMP-2]×[IGFBP7] serves as a sensitive and specific biomarker to predict AKI early after cardiac surgery and to predict renal recovery.

免疫原

HHHHHHHHGGQSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL

生化/生理作用

SILuProt IGFBP7 is a recombinant, stable isotope-labeled human IGFBP7 which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of IGFBP7 in mass-spectrometry. SILu Prot IGFBP7 is a protein consisting of 267 amino acids (including an N-terminal polyhistidine tag), with a calculated molecular mass of 28 kDa.

外形

Supplied as a lyophilized powder containing phosphate buffered saline.

法律信息

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.12

产品性质

质量水平200
生物来源human
重组expressed in HEK 293 cells
测定≥98% (SDS-PAGE)
形式lyophilized powder
效能≥98 Heavy amino acids incorporation efficiency by MS
technique(s)mass spectrometry (MS): suitable
适用性suitable for mass spectrometry (standard)
UniProt登记号Q16270
储存温度−20℃
Gene Informationhuman ... IGFBP7(3490)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品